What is so special about miconazole nitrate that pharmacists often say?
Release time:
2024-06-12
Many consumers go to pharmacies to consult gynecological drugs, especially fungal infections, and pharmacists will recommend miconazole nitrate antifungal drugs. So what's so special about miconazole nitrate?
Here we need to start with azole drugs. "azole" itself is transliterated as azole. azole drugs are divided into triazole and imidazole. we often say that miconazole nitrate, ketoconazole, econazole and so on belong to this category. basically, drugs with azole belong to broad-spectrum antifungal drugs. Today, we will focus on miconazole nitrate, which is the most widely used azole.
Everyone knows that fungus is a creature with very tenacious vitality. It can't be stopped at minus 40 degrees. It can still survive for a long time in a high temperature of 120 degrees. Even if it is separated from the human body, it is still toxic, so it is really infected. It has always been a very big problem. In the early 20th century, foreign pharmacists began to study antibiotic antifungal drugs. Until the 1970 s, the Belgian Janssen Company successfully researched and synthesized miconazole antifungal drugs, which made a big step forward in the study of anti-fungal drugs. The familiar miconazole (miconazole) was born at this time.
Miconazole nitrate belongs to imidazole antifungal agents, is efficient, safe, broad-spectrum antifungal drugs, its mechanism of action is to inhibit fungal cell membrane sterol synthesis, affect cell membrane permeability, inhibit fungal growth, leading to fungal death, so the miconazole drugs on pathogenic fungi almost have a role. Because it is widely used and entered the country earlier, it has a high reputation and is also a standing medicine for many modern families.
In order to promote better antifungal effect, miconazole nitrate has different dosage forms for convenient absorption and use, such as cream, powder, suppository, tablet, capsule, solution, etc. Different dosage forms, the scope of application is also different, such as miconazole nitrate suppository of miconazole is mainly suitable for the treatment of candidiasis vulvovaginitis and gram positive bacteria. Miconazole cream, this cream is mainly used to treat tinea corporis, tinea versicolor and candidiasis of the nails caused by fungal infections.
In modern clinical practice, although many drugs have "azole" in their names, "oxazole", "conazole" and "nitric acid" are actually different. They are similar in structure, but their pharmacological effects are completely different. Therefore, the diseases used for treatment are also different. Different types of antifungal drugs need to be selected according to the specific conditions of patients and used under the guidance of doctors to achieve the best results.
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