Imidazole antifungal drug mechanism of action
Release time:
2024-07-29
The mechanism of action of imidazole antifungal drugs is mainly to inhibit the growth of fungal cells, and then play an antifungal role. Imidazoles belong to a large class of antifungal drugs, including more drugs, according to their own circumstances prescribed medication.
Imidazole antifungal commonly used miconazole, bifonazole, clotrimazole, etc., these drugs are mainly used to treat fungal infections of the skin and mucous membranes, but also can be used to treat Candida infection of the skin. No matter which imidazole antifungal drug is selected, its mechanism is the same, which is to inhibit the biosynthesis of ergosterol in the fungal cell membrane, and affect the permeability of the cell membrane, so as to play the role of antifungal.
In clinical practice, imidazole antifungal drugs have external preparations, oral preparations, but also some injections, such as clotrimazole betamethasone cream, ketoconazole tablets, fluconazole injection and so on. Because each person's fungal infection area, depth is different, so according to their own situation to choose the appropriate dosage form of drugs.
People with fungal infections on the skin should do a good job of local hygiene care, because fungal infections are contagious and easy to recur, so they should keep a certain distance from other people's daily necessities. After the occurrence of fungal infection of skin and mucous membrane, do not use drugs blindly. Fungal infection is relatively stubborn in treatment. It is necessary to adhere to sufficient amount of medication to achieve good results. Therefore, it is suggested that patients should go to the dermatology department of the hospital to avoid delaying the disease.
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